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Vitamins Information (Home) > Quick Information > Arginine AKG (NO2 Compound) Arginine alpha-ketoglutarate (AAKG) is a compound made from the amino acid L-arginine and alpha-ketoglutarate, a substance formed in the body’s energy-generating process. AAKG is a popular supplement among bodybuilders and other athletes because of claims that it increases production of nitric oxide in muscles. Nitric oxide is known to have blood-flow-enhancing effects, which could in theory increase the delivery of oxygen and nutrients to exercising muscle. While L-arginine by itself is known to increase nitric oxide production, no research has been done to show that AAKG does the same. However, a preliminary report of a double-blind trial of AAKG suggested it might improve some measures of strength and power resulting from weight training.
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