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Vitamins Information (Home) > Side Effects > Fluoride Fluoride Side EffectsThe risks associated with fluoridation of the public water supply have been the subject of vigorous and often heated debate since fluoridation began in 1945. Although much research has been done regarding the safety of fluoridation, a recent review found all prior studies to be of sub-optimal quality and far from definitive. Some, but not all, studies have found a correlation between the amount of fluoride intake and increased risk of osteoporotic fractures. The validity of the studies that found increased risk of fracture in communities with fluoridated water has been questioned by some scientists. A pooled analysis of 29 studies on this issue concluded that there did not appear to be an increased risk of fracture in areas of water fluoridation. Dental fluorosis, a brown staining of teeth due to fluoride exposure during childhood, is the best-documented adverse effect of fluoride. At a water fluoride level of 1 part per million (or 1 mg per liter), roughly 13% will have fluorosis to an aesthetically concerning degree. Some scientists have concluded that water fluoridation is associated with an increased risk of bone tumors, although most others disagree. At the time of writing, there were no well-known drug interactions with fluoride.
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