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Vitamins Information (Home) > Side Effects > Methylsulfonylmethane
Methylsulfonylmethane Side EffectsAccording to some anecdotal reports, MSM has been used in human research for many years in amounts above 2000 mg per day with no significant adverse effects. However, diarrhea, skin rash, headache, and fatigue may be experienced in less than 20% of people, according to other anecdotal reports. Detectable levels of MSM in the brain of a person taking MSM supplements have been reported, but the significance of this finding, if any, is unclear. At the time of writing, there were no well-known drug interactions with methylsulfonylmethane.
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