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Vitamins Information (Home) > Sources > Pregnenolone
The cells of both the adrenal gland and the central nervous system synthesize pregnenolone. Human studies show there are much higher concentrations of pregnenolone in the nervous tissue, than in the bloodstream. Animal studies indicate the concentration of pregnenolone in the brain is ten-fold higher than that of other stress-related hormones (including DHEA). Pregnenolone is present in the blood as both free pregnenolone and a more stable form, pregnenolone-sulfate.
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